Meridia Reviews
Researchers
at Nova Southeastern University in Ft. Lauderdale, Florida, conducted
a double-blind, controlled study and found Meridia
(sibutramine) to be effective in reducing weight when it is used
along with a reduced-calorie diet, behavior modification, and
an exercise program. They also warned that some patients experience
a substantial increase in heart rate and blood pressure. For more
information on side effects associated with Meridia, visit Meridia
Side Effects.
The manufacturer
reports that weight loss was examined in eleven double-blind,
placebo-controlled obesity trials that lasted from 12 to 52 weeks
and used doses ranging from 1 to 30 mg 1 time daily. Compared
with patients who took placebos, those who took 5 to 20 mg of
sibutramine daily lost significantly more weight. Analysis of
data from three studies that lasted 6 months or longer indicates
that patients who lose at least 4 pounds during the first 4 weeks
of treatment on a given dose will most likely achieve significant
long-term weight loss on that same dose.
Studies show
that people who follow a low-calorie diet and take Meridia for
6 to 12 months lose about 11 lbs, while people who follow the
same low-calorie diet but do not take Meridia lose only about
2.2 lbs.
Approximately
50% to 60% of the people who take Meridia lose more than 5% to
10% of their body weight while taking the medication, compared
with about 20% to 30% of people who follow the low-calorie diet
only.
However, Meridia
doesn't work for everyone. Studies show that about 10% of people
do not lose weight while taking Meridia. If you have not lost
about 4 lb within the first month of treatment, Meridia may not
be an effective medication for you. For answers to frequently
asked questions about Meridia, visit Meridia
FAQ.
To be effective,
Meridia must be used along with a sensible eating plan, behavior
modification, and a regular exercise program. However, weight
loss may be temporary only, especially after the drug is discontinued.
To maintain
weight loss or to continue to lose additional weight after stopping
sibutramine, it is necessary to follow a sensible eating plan
and an exercise program.
To compare
prices of Meridia among several top on-line pharmacies, visit
Cheapest Meridia Online.
Partial
List of Reviews and Studies on Meridia:
Apfelbaum,
M., et al. Long-term maintenance of weight loss after a very-low-calorie
diet: A randomized blinded trial of the efficacy and tolerability
of sibutramine. American Journal of Medicine, 1999, 106:
179–184.
Bray, G.A.,
et al. Sibutramine produces dose-related weight loss. Obesity
Research, 1999, 7(2): 189–198.
Connoley,
I.P., et al., Thermogenic effects of sibutramine and its metabolites.
Br J Pharmacol, Mar. 1999, 126(6): 1487-95.
Hanotin, C.,
et al. Efficacy and tolerability of sibutramine in obese patients:
A dose-ranging study. International Journal of Obesity,
1998, 22: 32–38.
Heal, D.J.,
et a!., Sibutramine: a novel anti-obesity drug. A review of the
pharmacological evidence to differentiate it from d-amphetamine
and d-fenfluramine. Int J Obes Relat Metab Disord, Aug.
1998, 22(Suppl 1): S18-28.
Lean, M.E.J.
Sibutramine: A review of clinical efficacy. International
Journal of Obesity, 1997, 21: S30–S36.
Luque, C.A.,
and Rey, J.A., Sibutramine: A serotonin-norepinephrine reuptake
inhibitor for the treatment of obesity. Anni Pharmacother,
Sep. 1999, 33(9): 968-78.
Seagle, H.
M., et al. Obesity Research, Mar. 1998, 6(2): 115-121.
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